Subject(s)
Betacoronavirus/isolation & purification , Coronavirus Infections/complications , Exanthema/virology , Pneumonia, Viral/complications , Skin Diseases, Infectious/virology , Skin/virology , Angiotensin-Converting Enzyme 2 , Betacoronavirus/genetics , COVID-19 , Coronavirus Infections/diagnosis , Coronavirus Infections/genetics , Coronavirus Infections/virology , Coronavirus Nucleocapsid Proteins , Exanthema/diagnosis , Exanthema/genetics , Humans , Nucleocapsid Proteins/genetics , Pandemics , Peptidyl-Dipeptidase A/genetics , Phosphoproteins , Pneumonia, Viral/diagnosis , Pneumonia, Viral/genetics , Pneumonia, Viral/virology , RNA-Seq , SARS-CoV-2 , Single-Cell Analysis , Skin Diseases, Infectious/diagnosis , Skin Diseases, Infectious/geneticsSubject(s)
COVID-19 , Dermatology/methods , Photography , Referral and Consultation , Skin Diseases/diagnosis , Skin Diseases/therapy , Telemedicine/methods , Triage/methods , Acne Vulgaris/diagnosis , Acne Vulgaris/therapy , Alopecia/diagnosis , Alopecia/therapy , Delivery of Health Care , Dermatology/organization & administration , Eczema/diagnosis , Eczema/therapy , Humans , Intertrigo/diagnosis , Intertrigo/therapy , Primary Health Care , Psoriasis/diagnosis , Psoriasis/therapy , SARS-CoV-2 , Skin Diseases, Infectious/diagnosis , Skin Diseases, Infectious/therapy , Telemedicine/organization & administration , Telephone , United Kingdom , Urticaria/diagnosis , Urticaria/therapyABSTRACT
We identified severe acute respiratory syndrome coronavirus 2 RNA in an oropharyngeal swab specimen collected from a child with suspected measles in early December 2019, ≈3 months before the first identified coronavirus disease case in Italy. This finding expands our knowledge on timing and mapping of novel coronavirus transmission pathways.
Subject(s)
COVID-19 Nucleic Acid Testing , COVID-19/diagnosis , RNA, Viral/analysis , SARS-CoV-2/genetics , Skin Diseases, Infectious/diagnosis , COVID-19/virology , Child, Preschool , Humans , Italy , Male , Oropharynx/virology , Skin Diseases, Infectious/virologyABSTRACT
Numerous unexplained pneumonia cases were reported to the World Health Organization (WHO) by Wuhan, China, in December 2020. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a zoonotic pathogen, came into sight, spreading coronavirus disease 2019 (COVID-19) all over the globe. Association of cutaneous signs and symptoms with COVID-19 is being studied worldwide, principally, to determine if these dermatoses can help in early recognition of SARS-CoV-2 infection. These dermatological manifestations can range from erythematous rash, urticaria to livedo reticularis, and acrocyanosis in patients of all age groups. Correspondingly, dermatologists treating COVID-19 patients, suffering from inflammatory dermatoses, with biologics or immunomodulators should exert caution and use specific protocols to adjust the doses of these medications. Prevention of person-to-person transmission of COVID-19 is being promoted universally, with the use of personal protective equipment (PPE), hand washes, and hand sanitizers around the clock. However, an array of cutaneous adverse effects such as contact dermatitis, irritant contact dermatitis, friction blisters, contact urticaria, acne, and infections are associated with the use of PPE. Extra-pulmonary manifestations of COVID-19 are still emerging in the community, and physicians and researchers are working together globally to strengthen the clinical management of these patients. Cases of COVID-19 continue to rise across the world, and an unprecedented approach has been taken to develop effective vaccines and therapeutic strategies against existing and forthcoming mutagenic strains of SARS-CoV-2.